Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0348484
PubChem CID
Molecular Formula
C19H14ClNO4
Molecular Weight
355.777 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
OKFVCWAYHJMQFA-UHFFFAOYSA-N
InChI
InChI=1S/C19H14ClNO4/c20-13-8-9-15(19(23)24)16(10-13)21-18(22)11-25-17-7-3-5-12-4-1-2-6-14(12)17/h1-...
IUPAC Name
4-chloro-2-[(2-naphthalen-1-yloxyacetyl)amino]benzoic acid
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

39 41 0 0 0 0 0 0 0 0999 V2000
3.8345 -1.7708 -1.9112 O 0 0 0 0 0 0 0 0 0 0 0 0
4.7195 -1.1087 -1.0646 C 0 0 0 0 0 0 0 0 0 0 0 0
5.7778 -1.693...

Experimental Data

Activity Data

Target Ion Channel
Transient receptor potential cation channel subfamily M member 4
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 400 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.2
Holding Potential
Not specified
Temperature
Room Temperature
Test Method
Influx assay (sodium ion)
Test Species
HEK293 cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
25
Rotatable Bonds
5
logP
4.2089
Complexity
96.484
TPSA (Ų)
75.63
H-Bond Donors
2
H-Bond Acceptors
3
Ring Count
3
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